Research Summaries

Airnergy Research – Airnergy Studies and other Activated Oxygen Therapy Research and Information for users and practitioners:

Summary Results of Placebo Controlled Long-term Active Air Therapy Study of Chronic Obstructive Pulmonary Disease (COPD) Patients

Study conducted by Dr. Michael Kucera between March 2008 and March 2010

Over six months, a total of 24 patients were studied, all taking standard COPD treatments appropriate to the severity of their disease. Half were treated with placebo and half were treated (in addition to their usual treatments) with twice-daily sessions of Activated Oxygen Therapy (‘Active Air’). The patients treated with Activated Oxygen Therapy showed significant improvements in their objective parameters of FEV1% and FEV1/FVC% in addition to subjective improvement in their dyspnoea (breathlessness), reduced expectoration of mucus, they used their inhalers less and showed significant overall improvement based on the GOLD classification standard. Patients in the placebo group showed no improvements.

“These data suggest that activated air has significant potential for COPD treatment.”



Effects on Asthmatic Patients – Activated Oxygen Therapy

Study conducted by Dr Nyjon Eccles BSc MBBS PhD MRCP, May 2004

Six volunteers were recruited for a study of the effect of 4 sessions of 20 minute Airnergy sessions on various physiological parameters, namely Heart Rate Variability (HRV), Respiratory function in 2 asthma sufferers and Live blood morphology.

There was a significant expansion of the total HRV power during autonomic nervous system challenge indicating a positive effect on physiological reserve capacity. Both asthmatics demonstrated a 20% improvement in Peak Expiratory Flow Rate (PEFR) and improved subjectively. There was a consistent increase in white blood cell activity in all subjects as observed on Live Blood Microscopy but with one exception, no change in red blood cell morphology.

” The finding that PEFR increased would argue that the treatment was doing something to reduce airway resistance. A further study is needed in order to ascertain the exact mechanism of this action.”

Breathing of Singlet Oxygen Activated Air and the effect on blood parameters in healthy individuals.

Study conducted by Bjorn Carlmark, 1998 (Scandlab 30414)

Ten subjects were studied over a four week period. Each subject received 12-20 minutes Activated Oxygen Therapy three times a week for the duration of the study. Blood tests were carried out pre therapy, at 2 weeks and after 4 weeks. 32 different parameters were examined including cholesterol, triglycerides, glucose, calcium, potassium and sodium. Total Antioxidant Status (TAS) was also measured.

Total Antioxidant Status increased from a mean of 1.27 to 1.37 after 2 weeks and remained this high after 4 weeks of treatment.

All ten subjects showed a significant decrease in total serum cholesterol, a decrease of about 25% in serum triglycerides and a considerable decrease in serum urate / uric acid.


Report on a two-stage controlled study, using heart-rate-variability measurements (HRV) in respect of the effectiveness of the Airnergy+ Oxygen Therapy.

Study conducted by Ulrich Knop, 2003

” Treatment with Airnergy+ obviously and significantly achieves immediately an improved reaction to the metabolic sequence and, simultaneously an optimisation of the neurological control if all inner organs. Logically, this leads to a more stable basic health with increased reactivity. Organic assets are being spared, reserves of power are increased and the process of tissue ageing is slowed down. In the end this leads to a stabilisation and improvement of all organs and organic systems that are involved.” 

Another study on Activated Oxygen Therapy and the Autonomic Nervous System:

Jung K.: Energetisierung der Atemluft. Auszug aus Natur-Heilkunde Journal, 11/2008

In a randomised, placebo-controlled, double blind study on 40 sports students Hottenrott et al, investigated the effect of a single 21-minute Airnergy treatment in respect of an acute reaction on autonomic regulation. The starting hypothesis was that activation of the respiratory air with Airnergy has effects upon the cardio-respiratory system and that these would be measurable via the surrogate parameter of HRV. The study design included 3 phases: 10-minute rest phase, 21-minute intervention phase using Spirovital Therapy, 10-minute post treatment phase.

The results showed a significant interaction effect in the verum group comparing the intervention phase with the subsequent post intervention phase for the parameters LF (low frequency, sympathetic nervous system), HF (high frequency, parasympathetic nervous system) and the LF/HF ratio (sympathetic/parasympathetic). No difference was found for the CSI (cardio stress index). In the verum group LF (low frequency, sympathetic) increased very significantly after the intervention phase, whilst HF (high frequency, parasympathetic) fell significantly. There was no significant change for LF and HF in the placebo group. In both groups the average heart rate dropped significantly from the pre-phase to the intervention phase and in the post phase it remained at the same level as in the intervention phase.

The significantly higher HF percentage (high frequency, parasympathetic) during the intervention phase with the verum device compared to the placebo device and the subsequent drop in the HF percentage (high frequency, parasympathetic) with simultaneous drop in the LF percentage (low frequency, sympathetic) in the post phase clearly demonstrates the acute vagal effect of Spirovital Therapy upon autonomic regulation.

Influence on endurance levels of an Airnergy application prior to exertion.

Study conducted by Dr Elmar Wienecke, 2007.

With 15 amateur sportsmen as test subjects, the influence of a pre-exercise Airnergy treatment upon endurance performance was investigated in 2007 by Dr. Wienecke in the SALUTO Centre for Health and 30 Presentation of the study data Fitness in Halle/Westphalia, founded and run by him (14). The subjects completed a 60-minute session on a treadmill, after which they inhaled on a placebo or a verum Airnergy device, without knowing which. There was always one day without endurance loading between the cross-over inhalations. The results of this study showed a highly significant reduction in blood lactate values and heart frequency values after the use of Spirovital Therapy compared to the placebo treatment. In addition to this, the subjects described a clear improvement in performance after using Spirovital Therapy following unblinding.

Based on the positive results obtained, the same study was carried out with 16 subjects under identical conditions before a bicycle ergometer trial. The results of this test confirm the findings from the previous test. It can therefore be concluded that inhalation of Airnergy 60 minutes before an endurance activity brings about a saving in metabolic activity, reproducible in the reduction of the measurement parameters of blood lactate and heart rate. The author does not offer any hypothesis as to the possible underlying physiological-biochemical processes that could have produced these remarkable results.



Observations of patients with chronic fibromyalgia

Dr. Anders Willstedt, Sweden (who has already successfully treated over 600 patients with Fibromyalgia with Activated Oxygen Therapy), 1998

Twenty patients with a diagnosis of Fibromyalgia were given three Activated Oxygen Therapy sessions a week, over a period of 2 months (each for 20 minutes).

The observations were as follows:
5 patients ‘recovered’
13 patients experienced ‘significant improvement’
1 patient reported no changes
1 patient aborted treatment (for private reasons)

“The improvements consisted of:

• Improved attitude to life, recurring zest for life
• Reduction of pain and usage of medicaments
• Recreative sleep, less insomnia
• Improved productive efficiency
• Recurring motivation, strengthened vitality
• Improved gastrointestinal functions
• Improved visual faculty, without having a mist in front of the eyes
• Improvement in quality of hair and fingernails

At the beginning of treatment some patients reported temporary digestive problems, a few temporary moderate headaches.”

ME Research Study using the SoeMac

Extract from Interim Report by R. Dempster – July 2015 (credit to for online publication)

Summary findings so far.
Of the 12 people to complete the initial 8-week Study period (6 weeks with the SoeMac plus
2 weeks wash-out), all have shown some benefits or other, although we are not yet ready to
advise that in all 12, the benefits are conclusive. Improvements were specifically noted in
many of the Study group in better sleep, mental alertness and cognitive thinking. We are
very encouraged by the findings, and have extended the Study period, and observe
continued and progressive improvements. It is a very exciting time. Here are my notes of
what we have learnt so far:
Study overview.
We sought volunteers from the Nottingham and Mansfield ME support groups. The people
on the Study are mainly acute sufferers of the illness, are a variety of ages, and have
suffered for different periods of time. It was decided not to have a control group with
placebo machines, due to not wanting to waste a person’s time, in this initial study. 16
people applied for the study, and 12 play an active part. Of the other 4 people, 1 chose not
to start, one encountered problems in both using the SoeMac and recording the
information, so was discounted, and the other 2 were actually Fibromyalgia, and not ME,
sufferers (of these, 1 has shown benefits, 1 is neutral).
The study has not been finalised and there is some way to go before all the figures can be
analysed and full results reported. This first study period of 6 weeks with the SoeMac was
too short, and the time has been extended for some people. What we got was an indication
of the benefits, and now the longer Study period is giving far better, and consistent, results
and more information.
Future studies will need to last longer, probably for as long as 6-months, as it has become
clear that the Fatigue related conditions are complex, affect different people in different
ways, and respond to the SoeMac in different timescales.

The Body systems.
1. Systems related to detoxification of the body, in the removal of waste products and
toxic element build up, requires a lot of energy to remove some of these elements of
gas, ion channel flow, and chemical wastes from processes in the body.
2. The autonomic nervous system which monitors and controls all the back ground
functions and responses of both glands and organs. The study has noted there is a
homeostatic balancing to this system from the treatment which can help the heart,
lungs, stomach, brain, stress, memory and sleep to varying degrees.
3. The nervous system synapses in reducing pain and the messaging of the nerves
themselves are working better.
4. The lungs in function and clearance of mucus.
5. The blood circulation as a whole, but also in the smaller vessels, which also includes
the brain and allows the heart to function with less effort and the health of
haemoglobin to move through those smaller circulation systems.
6. Oxygen supply via the haemoglobin is noted to improve, perhaps due to the better
blood circulation and breathing. This is more important in supply to areas of the
brain which has been a problem for ME/CFS people. The Haemoglobin level was
tested (low) in 1 person before the Study, and then after using the SoeMac, the level
was normal, which may or may not be an indicator of a rebalancing of the
oxygen/haemoglobin system. Blood-oxygen saturation levels were tested on a
number of people within the study, and all were normal.
7. The muscles in ion channel flow and PH, which allow better recovery times from
8. Immune response to viruses is noted to be improved with regard to recovery times.
9. A general balancing and small increase in energy levels. Whether this is due to all of
the above or not is unclear, but there is an improvement when using the SoeMac.
Due to the nature of the illness affecting the whole body this may show a slow
progression that builds up over time.
10. A major metabolic boost in both energy and cognitive thinking can be produced by a
certain use of the SoeMac, which lasted from 2 hours to 4 days, without the normal
payback of fatigue or other side effects. It was possible to plan and repeat this
process, and create a positive spike in energy levels when required. This has only just
come to light with this study, and is a new development. The theory behind this is
quite straight forward, and is being researched further. We hope it will help future
users of the SoeMac to be more effective.
Study details.
Of the 12 people on the Study,
5 people have finished the 8 week study period, all showed positive indications to
different systems being affected: pain control, improved sleep, mental alertness,
breathing better, detox, slight energy uptake to varying degrees. Due to the short
time these people spent using the SoeMac, it is difficult to be categorical that their
improvements were obvious enough, but much was learnt from the results and
information given. This has been very valuable with regards to medication reactions,
life style impact, reaction to the symptoms of ME/CFS and areas in which the
SoeMac impacted the illness. There were no negative indications.
2 people are in the early stages of the study but have used the machine for a period
of time. Due to life getting in the way one person has only recently started the full
study, but has reported positive results helping her over a difficult period. The other
person has completed parts of the study and reported positive results, but due to
complications of food intolerance the results have been disrupted to the degree that
a full study will have to be restarted at a later time. I am continuing to work with her
to resolve her health problems.
1 person has been doing the study for a longer period and has reported positive
results, but I do not have all the study information paperwork, which I hope I can
resolve at a later date.
The last 4 people are on the extended research study period. (All have acute
ME/CFS). 3 people have been on the study from 15 to 18 weeks, all are now showing
positive overall results to general health for which the benefits are still increasing in
the areas which will be noted below, and the uptake in health increased from week
10, and although their health is still poor in normal terms, the results come as a
massive relief to them, and their ability to do more, think more clearly, and enjoy a
better quality of restful sleep, with reductions in pain and other benefits as part of a
stable progression. 1 person is at the 8 week period with some positive indications of
improvement that are not yet conclusive, but are likely to start in the weeks to
come, in line with those above.
Detailed observations from the group of 12.
1. Detoxification. 8 people, gas in early weeks, muscle clearance later weeks.
2. Breathing better. 3 people, not normally noticed if lungs have normal function. By
the 3rd- 4th week.
3. Sleeping better. 11 people, deeper longer more refreshing sleep, which leads to
feeling rested and alert when waking. Occurred in early weeks, and continued to
improve over time, giving increased benefits.
4. Blood circulation improvement. 7 people, 1 person showed major benefits from this
in circulation to feet and general health. All showed an increase in mild terms of
oxygen supply and wellbeing. From the early weeks onwards.
5. Pain reduction. 6 people, there was a general reduction in pain levels across the
group which was quite marked, and showed a gradual improvement from the early
weeks onwards. The pain level increased when usage of the SoeMac was stopped.
The lowering of meds was possible in some cases.
6. Alertness and cognitive thinking improvement. 9 people, the improvements to the
brain environment in blood supply, sleep, autonomic function and others. It did help
the mental process and ability in clearer thinking. The later weeks showed the
biggest benefits of this.
And from week 6 onwards.
7. Muscles relaxing better and less stiffness. 6 people, improved in longer term,
allowing for extra stretching exercise or use.
8. More stable activity levels, 4 people, allowing for new things to be done without the
fatigue payback. This includes both mental and physical activity.
9. Recovery from colds reduced by an estimated 50%. 2 people,
10. Heart and breathing response to exercise. 1 person,
11. Temperature control of body improvement. 2 people
12. Slightly better energy levels over the day from base line. 5 people,
13. Food intake and more interest in food. 2 people,
14. Improved migraine control. 1 person,
15. Better management of stressful conditions, 3 people,
16. Major metabolic boost to ME/CFS symptoms. 4 people have experienced this so far;
they say it is like going back to before their illness (2 people). The other two had a
large increase in energy levels beyond which they could ever hope for, which lasted a
number of days. At the end, it resulted in a slight tiredness, but there was no fatigue
crash or payback, which would have been the normal expectation. It seems this
process can be repeated and planned for.
Possible side effects and reactions noted.
1. Light headedness, dizziness. (mild) early weeks of study, which did wear off.
2. Headaches (mild) but only in early weeks.
3. Upset Stomach. 2 people, 1 of which had existing food intolerances, showed
sensitivity to the SoeMac. People with IBS were not affected to any noted degree.
4. Increased pain levels. 1 person. In first 3 weeks, and then resolved to lower levels,
and then improved altogether. Currently on the extended study period. (She did
comment that her body did normally react quite negatively to any new change).
5. 2 people reported being disturbed by the red light and noise from the machine when
sleeping, and it is deduced that those with hyper-sensitivity, may be disturbed by

Mr R Dempster